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Search Results for " retinoic acid "

20

Compounds

Cat No. Product Name Synonyms Targets
T1051 Retinoic acid Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin Retinoid Receptor , Endogenous Metabolite , PPAR , Autophagy
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat...
T21497 9-cis-Retinoic Acid Alitretinoin Apoptosis
9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can...
T77599 Methyl retinoate Retinoic acid, methyl ester Others
Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the le...
T37916 5,6-epoxy-13-cis Retinoic Acid
5,6-epoxy-13-cis Retinoic Acid is a metabolite of 13-cis retinoic acid.
T36382 All-trans-5,6-epoxy Retinoic Acid
all-trans-5,6-epoxy Retinoic Acid can be used in related research in the field of life sciences. Its product number is T36382 and CAS number is 13100-69-1.
T67921 Retinoic acid-d5 all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5 Retinoid Receptor
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a meta...
T1611 Isotretinoin 13-cis-Retinoic acid Retinoid Receptor , Endogenous Metabolite , Autophagy
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...
T3203 Methyl 13-cis-4-Oxoretinoate 13-cis-4-Oxo-retinoic acid Methyl Ester,4-Keto 13-cis-Retinoic Acid Methyl Ester Others
Methyl 13-cis-4-Oxoretinoate (13-cis-4-Oxo-retinoic acid Methyl Ester) is a retinoic acid metabolite in neuroblastoma.
T7408 All-trans-4-Oxoretinoic acid all-trans 4-Keto Retinoic Acid Endogenous Metabolite
all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid) is an active metabolite of vitamin A.
T3955 AR7 Retinoid Receptor
AR7 is a retinoic acid receptor α (RARα) antagonist.
TN6735 Bigelovin Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR 
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
T22843 HX 531 Retinoid Receptor
RXR antagonist
T15811 LY2955303 Others , Retinoid Receptor
LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).
TQ0097 AGN 193109 Retinoid Receptor , Autophagy
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
T17209 UVI 3003 Retinoid Receptor , Autophagy
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
T5341 WYC-209 WYC209 Apoptosis , Retinoid Receptor , Autophagy
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
T1330 Acitretin Ro 10-1670,Etretin Apoptosis , Retinoid Receptor , Autophagy
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
T23384 SR 11302 DNA/RNA Synthesis
SR 11302 is an inhibitor of activator protein-1 (AP-1).
T16832 S18-000003 ROR
S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). S18-000003 inhibits IL-17 production.
T7370 Talarozole R115866 Others , P450 , Retinoid Receptor , Autophagy
Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of...

Compounds

Retinoic acid
T1051
Synonym: Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin
Target: Retinoid Receptor, Endogenous Metabolite, PPAR, Autophagy
9-cis-Retinoic Acid
T21497
Synonym: Alitretinoin
Target: Apoptosis
Methyl retinoate
T77599
Synonym: Retinoic acid, methyl ester
Target: Others
5,6-epoxy-13-cis Retinoic Acid
T37916
Synonym:
Target:
all-trans-5,6-epoxy Retinoic Acid
T36382
Synonym:
Target:
Retinoic acid-d5
T67921
Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5
Target: Retinoid Receptor
Isotretinoin
T1611
Synonym: 13-cis-Retinoic acid
Target: Retinoid Receptor, Endogenous Metabolite, Autophagy
Methyl 13-cis-4-Oxoretinoate
T3203
Synonym: 13-cis-4-Oxo-retinoic acid Methyl Ester,4-Keto 13-cis-Retinoic Acid Methyl Ester
Target: Others
all-trans-4-Oxoretinoic acid
T7408
Synonym: all-trans 4-Keto Retinoic Acid
Target: Endogenous Metabolite
AR7
T3955
Synonym:
Target: Retinoid Receptor
Bigelovin
TN6735
Synonym:
Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR 
HX 531
T22843
Synonym:
Target: Retinoid Receptor
LY2955303
T15811
Synonym:
Target: Others, Retinoid Receptor
AGN 193109
TQ0097
Synonym:
Target: Retinoid Receptor, Autophagy
UVI 3003
T17209
Synonym:
Target: Retinoid Receptor, Autophagy
WYC-209
T5341
Synonym: WYC209
Target: Apoptosis, Retinoid Receptor, Autophagy
Acitretin
T1330
Synonym: Ro 10-1670,Etretin
Target: Apoptosis, Retinoid Receptor, Autophagy
SR 11302
T23384
Synonym:
Target: DNA/RNA Synthesis
S18-000003
T16832
Synonym:
Target: ROR
Talarozole
T7370
Synonym: R115866
Target: Others, P450, Retinoid Receptor, Autophagy
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